This course covers the exploitation of microbial cells, metabolites (i.e. enzymes), and gene expression in several areas of industrial, agriculture and environmental biotechnology, discuss the relationship between microbial and plant cell physiology and biotechnology, covering the recombinant DNA and fermentation technology, genetic manipulation, bioreactors designs, kinetic studies in biotechnology, biological remediation, plant tissue and cell culture, solid-state fermentation, process optimization and scale up procedure, modeling of biotechnological processes.