Use of economic theory and statistical methods to estimate economic models to enhance agribusiness decision-making is the focus. Concepts of simple and multiple regression and their related tests of significance of parameter estimates are presented. Econometric issues of functional form, relevant variables, predictive performance, model diagnostics, and major estimation problems in regression are examined. Non-parametric statistics, matrices, the related calculations and the related statistical tests are examined. Applications of techniques to agricultural economics and agribusiness problems are used.